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Circulation 147 , 338355

Based on in vitro studies, 6-shogaol with 20 uM doses can suppress UVB-induced inflammation, improve iNOS, COX-2, and TNF-, and increase antioxidant enzymes through the Nrf2 pathway in HaCaT cell culture, also can be a healing agent in cells undergoing oxidation so that it can prevent aging caused by free radicals (63)

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It has been proposed that the majority of MYB members of group C bind to MBS IIG and MrMYB1.1 was previously shown to be clustered related with AtMYB75 and AtMYB90 (Cao et al., 2021), both of which belong to the group C (Prouse and Campbell, 2012)